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Results for "

mRNA vaccines

" in MedChemExpress (MCE) Product Catalog:

29

Inhibitors & Agonists

21

Biochemical Assay Reagents

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153879
    C12-TLRa

    		Liposome Infection
    C12-TLRa is an adjuvant lipidoid. C12-TLRa acts as a structural component of LNP to enhance mRNA delivery. C12-TLRa substitution can increase antigen-specific antibody responses and B cell responses of clinically relevant mRNA-LNP vaccines .
    C12-TLRa
  • HY-134541
    SM-102
    5+ Cited Publications

    		 Liposome Infection
    SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102
  • HY-132289
    Lipid M

    		Liposome Inflammation/Immunology
    Lipid M (pKa: 6.75) can be used to deliver mRNA vaccine and yield a robust immune response with improved tolerability .
    Lipid M
  • HY-145969
    β-S-ARCA

    		Others Others
    β-S-ARCA is a mRNA 7-methylguanosine (m 7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines .
    β-S-ARCA
  • HY-151512
    A12-Iso5-4DC19

    		Liposome Inflammation/Immunology Cancer
    A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .
    A12-Iso5-4DC19
  • HY-138170
    ALC-0315
    5+ Cited Publications

    		 Liposome SARS-CoV Infection
    ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315
  • HY-46759
    Genevant CL1

    		Liposome Infection
    Genevant CL1 is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2].
    Genevant CL1
  • HY-46759A
    Genevant CL1 monohydrochloride

    		Liposome Infection
    Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .
    Genevant CL1 monohydrochloride
  • HY-W441014
    DSPE-PEG-NHS, MW 2000

    		Liposome Others
    DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
    DSPE-PEG-NHS, MW 2000
  • HY-W441012
    DSPE-PEG-NHS, MW 600

    		Liposome Others
    DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
    DSPE-PEG-NHS, MW 600
  • HY-W441016
    DSPE-PEG-NHS, MW 5000

    		Biochemical Assay Reagents Others
    DSPE-PEG-NHS, MW 5000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
    DSPE-PEG-NHS, MW 5000
  • HY-W441015A
    DSPE-m-PEG-NHS (MW 3400)

    		Liposome Others
    DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
    DSPE-m-PEG-NHS (MW 3400)
  • HY-150742
    ODN 2336

    		Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 2336 is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 induces the production of IFN-α. ODN 2336 up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 can be used as adjuvant of vaccines .
    ODN 2336
  • HY-150742A
    ODN 2336 sodium

    		Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 2336 sodium is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 sodium induces the production of IFN-α. ODN 2336 sodium up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 sodium can be used as adjuvant of vaccines .
    ODN 2336 sodium
  • HY-153380
    ALC-0315 analogue-2

    		Liposome Others
    ALC-0315 analogue-2 is an analogue of ALC-0315. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.
    ALC-0315 analogue-2
  • HY-148363
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate

    		Liposome Inflammation/Immunology
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate
  • HY-W440896
    DSPE-PEG-SH, MW 2000

    		Liposome
    DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
    DSPE-PEG-SH, MW 2000
  • HY-145973
    3'OMe-m7GpppAmpG

    m7(3'OMeG)(5')ppp(5')(2'OMeA)pG

    		 DNA/RNA Synthesis Others
    3'OMe-m7GpppAmpG is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG shows a significant translational efficiency. 3'OMe-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .
    3'OMe-m7GpppAmpG
  • HY-145973A
    3'OMe-m7GpppAmpG ammonium

    m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium

    		 DNA/RNA Synthesis Others
    3'OMe-m7GpppAmpG ammonium is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .
    3'OMe-m7GpppAmpG ammonium
  • HY-W590681
    113-O12B

    		Liposome Others
    113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
    113-O12B
  • HY-W440909
    DSPE-PEG-Cy3, MW 3400

    		Liposome
    DSPE-PEG-Cy3, MW 3400 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy3, MW 3400
  • HY-W440910
    DSPE-PEG-Cy3, MW 5000

    		Liposome
    DSPE-PEG-Cy3, MW 5000 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy3, MW 5000
  • HY-W440913
    DSPE-PEG-Cy5, MW 5000

    		Liposome
    DSPE-PEG-Cy5, MW 5000 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy5, MW 5000
  • HY-W440912
    DSPE-PEG-Cy5, MW 3400

    		Liposome
    DSPE-PEG-Cy5, MW 3400 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
    DSPE-PEG-Cy5, MW 3400
  • HY-W440919
    DSPE-PEG-Rhodamine, MW 2000

    		Liposome
    DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
    DSPE-PEG-Rhodamine, MW 2000
  • HY-153375
    LNP Lipid-5

    		Liposome Others
    LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .
    LNP Lipid-5
  • HY-153376
    LNP Lipid-6

    		Liposome Others
    LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .
    LNP Lipid-6
  • HY-153083
    COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)

    		SARS-CoV Infection
    COVID-19 Spike Protein mRNA will express COVID-19 spike protein, and suitable for detection of RNA delivery, translation efficiency, cell viability, etc. COVID-19 spike protein is the novel coronavirus pneumonia spike protein located on the membrane surface. COVID-19 spike protein undertakes the functions of virus binding to host cell membrane receptors and membrane fusion, thereby mediating the entry of COVID-19 virus into cells. COVID-19 spike protein is an important site of action for host neutralizing antibodies and a key target for vaccine design .
    COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)
  • HY-153235
    COVID-19 Spike Protein mRNA-LNP

    		SARS-CoV Liposome Infection
    COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing COVID-19 Spike Protein, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. COVID-19 Spike Protein is the novel coronavirus pneumonia spike protein located on the membrane surface. COVID-19 Spike Protein undertakes the functions of virus binding to host cell membrane receptors and membrane fusion, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design .
    COVID-19 Spike Protein mRNA-LNP

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